Professor Koleka Mlisana is the associate professor and Head of Medical Microbiology Dept at the Univ of KwaZulu Natal(UKZN) and National Health Laboratory Services (NHLS), Inkosi Albert Luthuli Central Hospital (IALCH) Academic Complex. Professor Mlisana talks about HIV/AIDS prevention and treatment in 2016, how it has advanced compared to 16 years ago and where we are headed in the future of HIV/AIDS research.